Natama et al. ovela eBurkina Faso wenze lolu cwaningo ukuze abheke imiphumela yokuchayeka kamalaleveva wangaphambi kokubeletha (PME) emazingeni amasosha omzimba kamama kumasampula egazi lentambo kanye nobungozi obulandelayo bemalariya ebuntwaneni. Ababhali basebenzise ucwaningo lweqembu lokuzalwa olwakhiwe ngaphakathi kocwaningo lomtholampilo lwe-COSMIC e-Burkina Faso ukuhlola izifo ze-Plasmodium falciparum ngesikhathi sokukhulelwa kanye neziqephu zikamalaleveva zasemtholampilo zezingane onyakeni wokuqala wokuphila. Besebenzisa ubuchwepheshe be-quantitative suspension array, bathole amazinga e-IgG kamama ne-IgG1-4 kuya ku-15 P. falciparum antigens egazini lentambo.
Okutholakele okungukhiye :
Ucwaningo lubuyekeze inani elibalulekile lezincwadi ezihlobene nomthelela wokuchayeka kukamalaleveva wangaphambi kokubeletha kumasosha omzimba kamama egazini lentambo kanye nokuba sengozini kamalaleveva ebuntwaneni. Izihloko eziyinhloko bekuwukuthi izinhlobo ezahlukene ze-PME ziwathinta kanjani amazinga amasosha omzimba komama, ukuthi amasosha omzimba kuma-antigen athile kamalaleveva ahlobene kanjani nengcuphe yokuthola umalaleveva wasemtholampilo, nokuthi angasho kanjani ukuthi umama uvikelekile yini kuwo noma maningi amathuba okuthi athole. umalaleveva womtholampilo. Izindikimba ezivamile ocwaningweni zazihlanganisa ukuhluka kwamazinga amasosha omzimba kamama asekelwe esigabeni se-PME, izindima zokuvikela zamasosha omzimba athile ngokumelene nomalaleveva womtholampilo, kanye nengozi eyengeziwe ehlobene namanye amasosha omzimba.
Izikhala Zocwaningo :
Ucwaningo luthole izindawo ezithile ezidinga ucwaningo olwengeziwe. Lokhu kuhlanganisa imiphumela yesikhathi eside yamasosha omzimba kamama evela egazini lentambo emandleni osana okuthola umalaleveva ngemva konyaka wokuqala wokuphila, indima yezinye izici, njengesimo sikamama sokuzivikela ezifweni, emazingeni amasosha omzimba kanye nengozi kamalaleveva, nendlela amasosha omzimba kamama. kuthinte ukusabela komzimba wosana kumalaleveva.
Ukutolika kanye Nemiphumela:
Okutholwe kulolu cwaningo kunemithelela ebalulekile ekuqondeni umthelela wokuchayeka kukamalaleveva wangaphambi kokubeletha kumasosha omzimba kamama kanye nokuba sengozini komalaleveva ebuntwaneni. Ukuhlonzwa kwamasosha omzimba athile kamama ahlotshaniswa nokuvikelwa noma ukwanda kwengozi kamalaleveva womtholampilo kugqamisa ukubaluleka kokuvikeleka komama ekubumbeni izimpendulo zokuzivikela ezinsaneni kumalaleveva. Ucwaningo olwengeziwe luyadingeka ukuhlola imiphumela yesikhathi eside yamasosha omzimba kamama, indima yezinye izici zikamama nezinsana, kanye nokungenelela okungase kube khona ukunciphisa ingozi kamalaleveva ebuntwaneni.
Umshwana wokuzihlangula: Lokhu okuqukethwe kukhiqizwe ubuhlakani bokwenziwa ngoLwesihlanu, 03 Meyi 2024 17:04:12 UTC. Nakuba kwenziwa yonke imizamo ukuze kuqinisekiswe ukunemba, kungase kube namaphutha ngezikhathi ezithile noma ukweqiwa.